RRT predictors (all shown as OR ) included female sex (2.27 ), younger age (0.83 per year), lower serum sodium (1.15 per mmol/L decrease), higher leukocyte count ≥13.0 × 10 3/μL (2.35 ) and creatinine (7.75 per 1 mg/dL increase) concentrations, and initial intravenous fluid administration ≥4 days following diarrhea onset (2.71 ). A longer interval from diarrhea onset to index visit was associated with reduced HUS risk (OR, 0.70 ). Predictors (all shown as odds ratio with 95% confidence interval ) of HUS included younger age (0.77 per year), leukocyte count ≥13.0 × 10 3/μL (2.54 ), higher hematocrit (1.83 per 5% increase) and serum creatinine (10.82 per 1 mg/dL increase), platelet count <250 × 10 3/μL (1.92 ), lower serum sodium (1.12 ). Of 927 STEC-infected children, 41 (4.4%) had HUS at presentation of the remaining 886, 126 (14.2%) developed HUS.
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